cleaning composition

专利摘要:
COMPOSITION, according to claim 14, characterized in that the proportion is from 1/19 to 1/1. The present invention relates to compositions which comprise the acyl glutamate salt as a primary surfactant or primary anionic surfactant and which still comprise specific preservation systems.
公开号:BR112017009623B1
申请号:R112017009623-4
申请日:2015-11-12
公开日:2020-12-08
发明作者:Joseph Oreste Carnali；Pravin Shah；Hongjie Liu
申请人:Unilever Nv；
IPC主号:

专利说明:

FIELD OF THE INVENTION
[001] The present invention relates to compositions for personal care. Compositions are isotropic personal care compositions based on water with a low pH. Compositions are preferably smooth (defined, for example, through low percentages in more rigid compositions). Preferably, the compositions have a good volume of foam (a sign of cleanliness for many consumers) and are stable. Preferably, the compositions are clear and have a pH of about 5.1 and lower, preferably of about 5.0 and lower (in general, the pH of the composition can be from about 3 to about 5, 0). At these pH levels, specific conservation systems can be used that provide excellent conservation while avoiding regulatory problems associated with other conservation systems normally used at a higher pH. The conservation systems of the present invention do not operate in the higher pH range. BACKGROUND OF THE INVENTION
[002] Synthetic detergents, such as cationic, anionic, amphoteric, non-ionic surfactants, are widely used in cleaning compositions for personal care. Anionic surfactants, in general, exhibit superior cleaning and foaming properties and therefore are normally incorporated into these compositions. Anionic surfactants, however, also tend to be irritating to the skin.
[003] Because consumers want the mildest compositions (that is, compositions that are not as rigid and irritating to skin and skin proteins), it is known to replace some anionic surfactant with other surfactants (for example, surfactants ionic and / or amphoteric). Another approach is to associate anionic surfactants with amphoteric or cationic compounds to create surfactant complexes (see US patent 4,443,362). These compositions often suffer from foaming and / or cleaning performance.
[004] Another approach to providing smoothness is to use the mildest anionic surfactants. Among such mild anionic surfactants that can be used are N-acylamino acids and their salts. The study “Surface Active N-Acylglutamate: Preparation of Long Chain N-Acylglumatic Acid” (M. Takehaka et al., Journal of American Oil Chemists Society, Volume 49, page 157 ff) cites patent JP 29444.1964) according to which acyl glutamates are believed to relieve skin irritations caused by other anionic surfactants, such as alkylbenzene sulfonates.
[005] As noted in US patent 6,703,427 de Schmucker et al., Such acylamino acids are contemplated as co-surfactants to alleviate the stiffness of primary anionic surfactants. Independently, as a primary surfactant (a “primary surfactant” is one that is present at a level of 50% or higher of all surfactants) in a surfactant cleaning system (as preferred for the compositions of the present invention) , or as the primary anionic surfactant (as a “primary anionic surfactant”, the surfactant is present at 50% or higher of all anionic surfactants; however, surfactants other than anionic surfactants in total may comprise more than 50% of the surfactant system total or less than 50% of all anionic surfactants in the system), it is expected that this surfactant is deficient in foam and / or cleaning in relation to the use of other anionic surfactants in the same composition. In addition, acylamino acids are difficult to solubilize at lower pH ranges, since the molecule will tend to precipitate. In general, it would not be envisaged to use acylamino acids, such as glutamate at a low pH and, normally, the glutamate salt precipitates at about pH 5.5 and below. As such, such glutamate salt molecules would not be contemplated for use in isotropic liquids (where solubility is necessary to ensure good clarity) at any significant level. In particular, they will not be contemplated for use as a primary surfactant, or as a primary anionic surfactant and in which, simultaneously, the amount of glutamate is preferably equal to or greater than any other single surfactant present. That is, according to the present invention, if the glutamate salt is a primary anionic surfactant, but the total sum of non-anionic surfactants is greater than that of the anionic surfactant, the glutamate salt must be present in an amount equal to or greater than any other surfactant present. It is preferably that the glutamate salt is present as the primary surfactant.
[006] Therefore, the use of acyl glutamate would not yet be contemplated (unless otherwise specified, the term "glutamate" or "acyl glutamate" will be used to refer to the glutamate salt) as the surfactant primary or as the primary anionic surfactant (where glutamate is simultaneously present in an amount equal to or greater than any other single surfactant present), since glutamate does not structure itself (for example, the self-structure) as easily as other surfactants and therefore, it can make it more difficult to suspend particles and other beneficial agents. As Depositors noted in a copending patent application, it is not easily clear how to structure with external structuring agents while maintaining a relatively clear isotropic liquid, especially at a low pH (for example, 6.5 and below, preferably 6 , 0 and below). The pH of the composition of the present invention is about 5.1 and lower. Depositors have applied for a copending patent in respect of compositions, in which glutamate is the primary surfactant (and, by definition, the primary anionic surfactant) and in which specific structuring polymers are used to provide enhanced liquid structure while maintaining the desired clarity (at a low pH of 6.5 and lower, preferably 6.0 and lower, preferably 4.0 to 6.0). Depositors filed a second copending patent application that is similar to the one mentioned above, but slightly broader in that it does not focus on structuring agents.
[007] Since acyl glutamate surfactants are not the type of anionic surfactants that provide superior foaming, since they do not easily solubilize (at a lower pH) and since they do not self-structure as well as other anionic ones , such surfactant would not be considered for use in a low pH liquid cleaning composition (pH 6.5 and below) as a primary surfactant or as a primary anionic surfactant, but in which the amount of glutamate is equal to or greater than any other single surfactant gift. In particular, they would not be contemplated for use as a primary surfactant or primary anionic in aqueous based cleaning compositions while retaining the ability to maintain good stability and clarity values.
[008] In the present invention, an even lower pH is contemplated. The present invention contemplates the use of specific conservation systems that would not work effectively at a higher pH. The systems of the present invention are desired since many preservatives used at a higher pH are associated with regulatory problems in jurisdictions where they have been or may one day be banned.
[009] In an unexpected way, Depositors have discovered that it is possible to formulate isotropic compositions based on water with a low pH (which remain clear and stable), in which acyl glutamate is the primary surfactant (systems of preference); or the primary anionic surfactant and simultaneously present in an amount equal to or greater than any other single surfactant present and in which the specific conservation systems observed can be used. Preferably, the pH of the composition is about 5.1 and lower. Most preferably, the pH is 3 to 5.1. Most preferably, the pH is 3.5 to 5.0, most preferably 4.0 to 5.0. Preferably, the composition is visibly clear (isotropic). Preferably, the composition is a clear single-phase composition (single-phase that is isotropic), where clarity is defined by an absorbance value of 1.0 or less, preferably 0.5 or less (for example, 0.01 to 0.5), more preferably 0.2 and less when measured at a wavelength of 550 nm.
[010] In addition, Depositors have found that when the amount of shortest chain glutamate (as a percentage of all glutamate) is minimized (to ensure good foaming) and the percentage of glutamate in relation to the co-active is maximized (savings in the cost of using the surfactant, surprisingly keeping the isotropic compositions clear, of low pH), the preferred compositions are found. In preferred systems, glutamate is the primary surfactant (present at a level of 50% or higher, preferably 55% or higher of all surfactants). Preferred systems that comprise glutamate and special co-active agents are also described.
[011] In a copending patent application, Depositors describe the compositions in which specific polymers can be used to further ensure that stable isotropic liquids are formed at relatively low pH (pH 6.5 and below, preferably 6.0 and preferably pH 5.5 and below), while maintaining a defined level of clarity. Such stable and clear compositions are not expected to form in systems where glutamate is the primary surfactant or the primary anionic surfactant while simultaneously present in an amount equal to or greater than any other single surfactant present. A second copending patent application is slightly broader in that it does not concern such specific structural polymers.
[012] A variety of compositions have been described in which glutamate is widely described.
[013] In U.S. patent 6,284,230 to Sako et al., A wide number of surfactants, including glutamates, are widely believed to be used as a primary anionic surfactant. From the examples, however, it is evident that when glutamate is used (Examples 1 to V), it is not the primary surfactant (ammonium sulfate in Examples I to V) and it is not the primary anionic surfactant. In Example VI, sarcosinate (the different acyl amino acid with a single carboxylic acid group) is the primary surfactant. It is never an acyl amino acid that has two carboxylic acid groups (such as glutamate) used as a primary surfactant or as a primary anionic surfactant in which glutamate is used in an amount equal to or greater than any other single surfactant present.
[014] The patents US 2004 / 0.258.807 and US 2011 / 016.506 are two other examples of references that widely describe glutamates, but again it is evident that glutamates are never used as primary surfactants; or as a primary anionic surfactant and in which glutamate is simultaneously present in an amount equal to or greater than any other single surfactant present in the composition.
[015] The shampoo compositions of the US patent 2005 / 034,895 comprise the surfactant, microbiological control agent, rheological additive, conditioning agent and solubilizer. Surfactant compositions include mixtures of glutamate and other surfactants (see Examples 2 to 5), but glutamate is never the primary surfactant or primary anion in which it is used in amounts equal to or greater than any other single surfactant in the composition.
[016] WO 2010/069500 describes in Example 1, Composition E, a composition that has 3.5% glutamate, 3.5% sarcosinate, 8.5% betaine and 2.5% glucoside. In this composition, glutamate is a primary anionic (it is present at a level of 50% anionic), but it is not present in an amount equal to or greater than any other single surfactant present (for example, betaine is the largest surfactant present) . It is also not the primary surfactant.
[017] The present invention, as noted, requires that glutamate be the primary surfactant (preferred embodiment); or present as a primary anionic surfactant while simultaneously being used in an amount equal to or greater, preferably greater than any other single surfactant present in the composition. In such systems, the pH is low enough that specific conservation systems can be used. Due to the reasons mentioned above, the formation of such a system would not be contemplated since it is believed that systems in which glutamate is used (especially as a primary surfactant) in relatively large quantities would compromise the formation of compositions that are clear (isotropic) , have good foaming, and are stable. BRIEF DESCRIPTION OF THE INVENTION
[018] The present invention relates to compositions comprising: (1) from 0.5 to 35% of a surfactant system in which the anionic surfactant is present from 0.5 to 25%, preferably from 1 to 15% by weight of the total composition and where: (a) the acyl glutamate salt is present at 50% or higher than all the surfactant present (“primary surfactant”); or (b) is present at a level of 50% or greater of the anionic surfactant (preferably, the acyl glutamate salt comprises an amount greater than 50% by weight of the anionic, more preferably, greater than 60% by weight of the total anionic) and simultaneously present in an amount equal to or greater than any other single surfactant present in the composition (“primary anionic surfactant”); (2) from 0% to 20%, preferably from 0.5 to 15% by weight of a co-surfactant selected from the group consisting of non-ionic, cationic and amphoteric surfactants and their mixtures (preferably, co-surfactants comprise the amphoteric surfactant, optionally which still comprises the non-ionic, preferably, the amphoteric comprises 1 to 10% by weight of the total composition); (3) optionally, from 0 to 30%, preferably from 0.1 to 10%, more preferably, from 0.1 to 5% of a beneficial agent for the skin or hair; (4) from 0.01 to 1% by weight of an organic acid having a pKa between about 4.0 and 5.5; and (5) water balance - where the pH is about 5.1 and lower, preferably the pH is about 5.0 and lower, most preferably, where the pH is about 3 to about 5.1, even more preferably, from 3.5 to 5, even more preferably, from 4.0 to 5.0.
[019] Regarding the use of oil or optional emollient of the component (3), the Depositor's first observation that the present invention can be defined as a surfactant chassis that is based on acyl glutamate as a primary surfactant or anionic surfactant primary. The surfactant chassis is preferably a stable, single-phase, isotropic composition, in an optical, clear way. However, when certain optional components (for example, certain oils or emollients) are added to the surfactant chassis, they may not be completely miscible with the stable, isotropic surfactant chassis and may make the resulting complete formulation anisotropic (for example, the composition it is no longer “clear”).
[020] Therefore, the present invention can comprise a complete formulation that does not contain the oil or emollient; or that contains a sufficiently low amount of oil or emollient; or that contains an oil or emollient that is miscible with the surfactant chassis so as not to become anisotropic as mentioned above. This formulation is a stable, single-phase composition that is clear (isotropic), as defined by an absorbance value of 1.0 or less than a defined wavelength.
[021] The compositions of the present invention may preferably comprise an agent of immiscible benefit. The present invention also comprises a complete formulation which is anisotropic (optically, not clearly), but which is formed from the combination of (1) a stable, single-phase, surfactant chassis, which preferably, optically, it is clear; and (2) the optional ingredient (s) present in sufficient quantity to make the final complete formulation anisotropic. A final anisotropic formulation that is not formed from the stable, single-phase, optically clear, clear surfactant chassis is not considered part of the present invention. Specifically, a composition that is anisotropic before adding, for example, emollient or oil does not form part of the present invention.
[022] Preferably, the compositions of the present invention (isotropic in full formulation or isotropic in chassis formation and anisotropic after the addition of certain benefit agents) are, or are formed from, single-phase isotropic systems. Preferably, the compositions (again, as a final composition, or as isotropic chassis before the addition of potential anisotropic forming agents) maintain optical clarity. Preferably, the compositions (such as final isotropic composition or isotropic chassis) are single-phase systems that maintain optical clarity as defined herein. Preferably, optically clear, single-phase systems are stable and maintain a single, optically clear phase under ambient conditions (about 25 ° C) for a period of one month or longer, preferably up to about one (1) year.
[023] In the typical preferred compositions of the present invention, the amount of glutamate surfactant is equal to or in excess of all other surfactants ("primary surfactant"); it can also be present at 50% or higher than anionic and simultaneously in an amount equal to or greater than any other single surfactant (“primary anionic surfactant”). Even if the sum of surfactants other than anionic forms more than 50% of the surfactant system, glutamate must be present in an amount equal to or greater than any other single surfactant. Preferably, however, it is that glutamate is the primary surfactant. Also preferably, it is to maximize the amount of glutamate used and minimize the use of cotensoactives.
[024] Some compositions of the present invention may contain from 0 to 10% by weight, preferably from 0.1 to 10% by weight, more preferably from 0.5 to 7% by weight of the structuring agent. Such a structuring agent can be the water-soluble or water-dispersible polymer which can be a cationic, anionic, amphoteric or nonionic polymer to enhance the viscosity and stability of the cleaning agent and is selected from the group consisting of carbohydrate gums; modified and unmodified starch granules; polyacrylate and methacrylate polymer and copolymer; cationic polymers including modified cationic polysaccharide, modified cationic cellulose and synthetic cationic polymers. The depositors' copending patent application describes special polymers that define an enhanced stability benefit. As indicated, the structuring does not need to be present, although it is preferably to stabilize the composition and assist in suspending, especially to suspend oil-soluble emollients. In a related copending patent application, Depositors claim compositions that comprise specific structurants that surprisingly maintain relatively isotropic liquids that are stable, all at a defined low pH range.
[025] The compositions of the present invention can comprise water-soluble or oil-soluble skin or hair benefit agents. These can be present at levels from 0 to 30%, preferably from 0.1 to 20% by weight, more preferably from 0.1 to 10% by weight of the total composition. Some compositions comprise water-soluble polyhydric alcohols. Water-soluble skin benefit agents preferably include glycerin, sorbitol and polyalkylene glycols (a polyalkylene glycol is preferably polyethylene glycol) and mixtures thereof. Preferably, the oil-soluble emollients comprise 30% or less, preferably 10% or less, preferably 5% or less (for example, from 0.1 to 5% by weight) of the composition. In some preferred embodiments, the oil-soluble emollient or oils are absent.
[026] In the absence of immiscible benefit agents (such as oil-soluble emollient or oils), the final compositions are clear (isotropic). They can remain that way if the quantities of immiscible ingredients are small enough. However, although the surfactant chassis is clear, the present invention also contemplates complete formulations that can be anisotropic but are formed from the combination of isotropic surfactant chassis and sufficient amounts of immiscible beneficial agent to make the complete formulation anisotropic. DETAILED DESCRIPTION OF THE INVENTION
[027] The present invention relates to low pH cleaning compositions, preferably water-based and clear, in which the acyl glutamate salts are present as a "primary surfactant" or, when the glutamate salts are "surfactant" primary anionic ”(although non-anionic surfactants may be present in an amount greater than 50% of all anionic surfactants) and are simultaneously present in an amount equal to or greater than any other single surfactant present. When glutamate is not present in an amount equal to or greater than any other single surfactant, such a composition is not intended to be encompassed by the compositions of the present invention.
[028] More specifically, these compositions (which, in general, are claimed in a copending patent application) comprise specific preservative systems that are especially effective in the low pH isotropic compositions of the present invention. The use of such conservation systems makes it possible to avoid other systems normally used in higher pH systems, but which may also be subject to regulatory challenges in some jurisdictions.
[029] Whether or not glutamate is the primary surfactant or the primary anionic surfactant simultaneously present in amounts equal to or greater than any other single surfactant, it is observed that glutamate necessarily comprises 50% or more of all anionic surfactants present and, as observed, is present in an amount equal to or greater, preferably greater than any other single surfactant in the composition. Due to the properties of glutamate noted above, it would not have previously been contemplated to form low pH compositions in which glutamate is the primary surfactant or primary anionic surfactant while maintaining the stable, isotropic, stable, single phase formulation. In some preferred compositions, the amount of short-chain glutamate (C10 or less) is minimized (to enhance foaming). In some preferred compositions, special structuring agents are used to intensify structuring (maintaining clarity), even at very low pH. These isotropically clear single-phase compositions are also preferably stable as defined above.
[030] Although glutamate surfactants are milder than other anionic surfactants, they usually do not foam and do not purify. Like all acylamino surfactants, acyl glutamates are also difficult to solubilize at low pH and, therefore, would not be contemplated for use in clear (isotropic) low pH compositions (ie, lack of solubility would be susceptible to affect clarity), especially at the high levels of glutamate surfactant required in the present invention. This is especially true when glutamate is the primary surfactant.
[031] Unexpectedly, at the moment the Depositors produced the stable and clear isotropic compositions (isotropic), of low pH, (as the final formulation or as the surfactant chassis before the addition of anisotropic inducing agents) in which the glutamate is the primary surfactant or primary anionic surfactant and present in an amount equal to or greater than any other single surfactant and comprising specific conservation systems highly effective in these clear, low pH isotropic compositions. The preferred compositions maximize the amount of glutamate used (as a percentage of the total surfactant) in order to minimize the costly co-surfactant. In addition, the compositions preferably minimize the amount of shorter chain length glutamate used and therefore intensify foaming. Finally, in other preferred compositions (as claimed in the copending application), the use of specific structuring agents allows the use of maximum amounts of glutamate in clear single-phase compositions (as a final composition or as a surfactant chassis) and especially at low pH ( for example, 5.1 and below, preferably 5.0 and below). In some preferred systems, the amount of beneficial agent, especially the oil-soluble emollient, is minimized (from 0 to 30%, preferably from 0 to 10%, most preferably from 0 to 5 %, most preferably still absent).
[032] More specifically, the compositions of the present invention comprise: - as indicated, the amount of glutamate can be such that it is the global primary surfactant, or the glutamate can be the primary anionic surfactant, while the amount of surfactants other than anionic is in excess of glutamate. When it is the “primary anionic surfactant”, but the surfactant system has an amount less than 50% of anionic surfactant in general, the glutamate must be present in an amount equal to or greater than any other single surfactant present in the composition.
[033] Furthermore, the compositions of the present invention are clear isotropic single-phase (isotropic) solutions. That is, there is a single clear phase (instead of a single phase that is clear as part of a multi-phase solution). The phase is stable (it does not break into multiple phases). "Clearness" is understood to have an absorbance value of 1.0 or less, preferably 0.5 or less, more preferably 0.2 and less when measured at a wavelength of 550 nm.
[034] If the benefit agent component (2) is not completely miscible in the surfactant chassis of (1), the composition may be anisotropic. However, the present invention is defined by the presence of component (2) that is miscible so that the final formulation is isotropic or, by the final anisotropic composition that was formed from the combination of component (1) isotropic chassis and component benefit (2). The main part for the present invention, however, is the formation of the final composition (isotropic or anisotropic from an isotropic chassis defined by the components (1, 3 and 4)) that have a pH and stability, as well as phase characteristics only clear, defined isotropic. SURFACE SYSTEM ANIONIC SURFACE
[035] A major part of the present invention is that it is present from 0.5 to 35% by weight of the total composition of a surfactant system in which the anionic surfactant comprises from 0.5 to 25% by weight of the total compositions and in whereas the acyl glutamate salt comprises 50% or more of all surfactants ("primary surfactants"); or 50% or greater, preferably 60% or greater by weight of the total anionic surfactant present (even if the total anionic is less than 50% of the total surfactant) and is present in an amount equal to or greater than any other single surfactant in the composition. Preferably, the anionic surfactant comprises from 1 to 15% by weight of the total composition, more preferably from 2 to 12% of the total composition. In some compositions, anionic comprises from 5 to 12% by weight of the total composition and surfactants that are not anionic comprise from 1 to 7% by weight of the composition. The amount of glutamate should always be maximized and, as noted, even if other surfactants are present in amounts greater than anionic (for example, when glutamate is not the “primary surfactant”), glutamate is present at 50% or higher anionic surfactant and is present in an amount equal to or greater than any other single surfactant present.
[036] The acyl glutamate salt used in the composition of the present invention has a structure as follows:
-Note that one or the other structures will occur at the pH levels of the present invention (pH 5.1 and below, preferably about 3 to about 5.1) and that at a higher pH (for example, 8 or 9), some disal is also present), - where R is an alkyl or alkenyl group (in general, saturated although some unsaturated, for example oleoyl) may be present containing 8 to 20 carbons, preferably 8 to 16 carbons, more preferably 10 to 14 carbons. Preferably, R is predominantly a mixture of C10-C14. As indicated above, for preference levels of foaming, it is preferably to minimize the amount of shorter chain length (eg C8-C10) and maximize the longer chain length, eg C12-C20 preferably C12-C16.
[037] Although C10 should be minimized, it will be observed, at least in some embodiments of the present invention, that the ratio of C10 to C12 should be at least 1/5, possibly 1/3 and higher (partly depending on of the co-surfactant used with the glutamate salts) to ensure isotropic formation. Preferably, the proportion should not be greater than 1 to 1, regardless of the co-active agent used (if present) with the glutamate salts.
[038] As used in the examples, a cocoyl chain length distribution is usually defined as follows: 13% C8-C10, 50% C12, 18% C14, 8% C16 and 11% higher or equal to C18, (http://coconutboard.nic.in/English-Article-Gopalakrishna-CFTRI.pdf), as preferably in the present.
[039] M is a solubilizing cation such as, for example, sodium, potassium, ammonium or substituted ammonium. Preferably, the cation is sodium or potassium, more preferably sodium. Preferably, it is the sodium salt.
[040] The pH of the overall composition is usually about 5.1 and lower, preferably about 5.0 and lower. Preferably, the pH is 3 to 5.1 and more preferably 3.5 to 5.0. Most preferably, the pH is about 4 to about 5
[041] The pKa of the acyl glutamate salt is relatively low (about 5). Depositors surprisingly found that the relatively large amounts of glutamate used can be solubilized, thus allowing them to take advantage of the smoothness of this anionic surfactant compared to other anionic surfactants.
[042] In addition, surprisingly large amounts of glutamate can be solubilized at low pH, thus allowing the formation of clear, single-phase isotropic compositions that are also mild.
[043] Clear and mild cleaning agents are seen as highly desired by consumers. By "clarity", Depositors mean having an absorbance value of 1.0 or less, preferably 0.5 or less, more preferably 0.2 or less when measured at a wavelength of 550 nm. As indicated above, the clarity values define the surfactant and water chassis. The composition can maintain clarity (remain isotropic) after the addition of the beneficial agent, but even if the final composition is anisotropic, if the starting frame is isotropic, as defined, it will be within the definition of the present invention.
[044] Although the acyl glutamate salt can be used as the only anionic surfactant in the total composition, it is desired to use other anionic surfactants, subject to the levels defined in the present. A preferred co-ionic (as opposed to co-active 1 (b)) is sarcosinate (the C10-C14 acyl sarcosinate alkyl salt is a sarcosinate of preference, where the salt is defined as in M above). Another preferred co-ionic is a taurate. Preferably, it is a C10-C14 acyl taurate salt (eg, sodium cocoyl methyl taurates). In general, preferably, it is not to use salts that would tend to precipitate at lower pH values. Therefore, it is preferably to minimize, for example, the amount of acyl glycinate (greater than 1.0%, preferably greater than 0.5%, preferably completely absent).
[045] In general, sarcosinate has the formula: -R2 CON (CH3) CH2CO2 M;
[046] Taurates have the formula: -R2 CONR3CH2CH2SO3 M -where R3 is methyl
[047] Glycinates have the formula: -R2 CONHCH2CO2 M -R2 above is alkyl or alkenyl containing from 8 to 22 carbons, preferably from 12 to 18 carbons; and - e M is the solubilization cation, as defined above.
[048] The compositions of the present invention may have low levels of alkyl sulfate ether, for example, sodium lauryl ether sulfate. The term "low" means less than 20% anionic, preferably less than 10%, preferably less than 5%. In some embodiments, the compositions contain less than 0.5% alkyl sulfate ether and in some there is substantially no alkyl sulfate ether. These types of sulfates are preferably minimized since they are less mild than other surfactants. COTENSOACTIVE
[049] A second component of the present invention can comprise from 0% to 20%, preferably from 0.5 to 15% by weight of the total composition of a surfactant coagent selected from the group consisting of non-ionic, cationic surfactant and amphoteric and their mixtures.
[050] Preferred co-active agents are amphoteric or zwitterionic surfactants. Preferably, co-active agent is amphoteric.
[051] This general class of amphoteric detergents has the following general structure:
-in which R is an alkyl or alkenyl radical with 7 to 17 carbons or a carboxamido functional group of the general structure
-in which R1 is an alkyl or alkenyl radical with 7 to 17 carbons and R4 is an alkyl, hydroxyalkyl or carboxyalkyl radical with 1 to 3 carbons. Each of R2 and R3, independently, is a proton, an alkyl, hydroxyalkyl, or carboxyalkyl radical with 1 to 3 carbons, or is completely absent, subject to the following restrictions.When each of R2 and R3, independently, is a radical alkyl, hydroxyalkyl or carboxyalkyl, nitrogen in a quaternary amine and is a cationic charge center.When one of R2 or R3 is an alkyl, hydroxyalkyl or carboxyalkyl radical and the other is a proton or is completely absent, nitrogen is an amine tertiary. At a pH well below the pKa of the tertiary amine, the other at R2 or R3 will be a proton and the amine will be a cationic charge center. At a pH well above the pKa of the tertiary amine, the other of R2 or R3 will be completely absent and the amine will be a center of neutral charge.
[052] Examples of amphoteric preference mentioned above include cocoamido propyl betaine (CAPB), C10-C14 alkyl betaine, the C10-C14 alkyl amphocetate salt (for example, lauroamfacetate) and mixtures thereof.
[053] Another class of amphoteric detergents are sultains with the following general structure:
-in which R is an alkyl or alkenyl radical with 7 to 17 carbons or a carboxamido functional group of general structure o
- where R1 is an alkyl or alkenyl radical with 7 to 17 carbons and R4 is an alkyl, hydroxyalkyl or carboxyalkyl radical with 1 to 3 carbons. Each of R2 and R3, independently, is an alkyl, hydroxyalkyl, or carboxyalkyl radical with 1 to 3 carbons, so that nitrogen in a quaternary amine and is a cationic charge center. A preferred amphoteric surfactant in this class is cocamidopropyl hydroxy-sultaine (CAPHS), lauramidopropyl hydroxy-sultaine (LAPHS) or lauryl hydroxy-sultaine (LHS).
[054] A preferred combination of the present invention is the glutamate salt and the sarcosinate salt as anionic surfactants in combination with the anfoacetate salt (preferably the C10-C14 anfoacetate) as a co-active agent. A preferred combination comprises 3 to 8% by weight of the total composition of the glutamate salt, 1 to 3% by weight of the total composition of the sarcosinate salt (where, preferably, glutamate is the primary or anionic surfactant) , as defined above) and from 3 to 8% by weight of the total composition of the anfoacetate salt (especially, the alkali metal salt of acyl anfoacetate). As previously mentioned, glutamate must be present in an amount equal to or greater than any other single surfactant present.
[055] A main aspect of the compositions of the present invention is that (as a complete isotropic composition or as a surfactant chassis before the forming composition) they are stable, clear, single-phase isotropic liquids, especially at pH values of 5.1 and lower, preferably the pH of 3.5 to 5.0, more preferably of 4.0 to 5.0.
[056] Glutamate salts can comprise a mixture of chain lengths. As indicated, it is usually preferable to minimize the shorter lengths of C8 and C10 since they also do not normally foam.
[057] The use of a mixture of C10 and cocoyl also helps to prolong the regions of isotropic clarity compared to mixtures, where only, for example, C10 and C12 are used. This suggests that some amount of C14 to C20 may also be preferred.
[058] In some compositions, the surfactant system comprises a mixture of C10 and cocoyl glutamate in conjunction with the alkali metal salts of anfoacetate.
[059] Mainly, the present invention refers to the unexpected observation that glutamate can be used as a primary surfactant; or as a primary anionic surfactant and is used simultaneously in an amount equal to or greater than any other single surfactant present in the composition. Preferably, it is used as a primary surfactant in single-phase compositions of low pH to an aqueous base that has visual clarity. Even if the added benefit agent causes the formation of a final anisotropic composition, the surfactant chassis, prior to the addition of anisotropic forming agent, is isotropic. Due to its low pH solubility, it is therefore possible to produce a mild composition (surfactant acylamino which is smooth) which is also optically, clear (isotropic). At the same time, since these are low pH compositions, they can provide the antibacterial effect, avoiding the use of certain antibacterial agents that are restricted in certain parts of the world. In fact, the present invention relates to the use of specific conservation systems effective at low pH and which would normally not be used in higher pH systems.
[060] Therefore, anisotropic compositions (formed using the isotropic chassis based on glutamate) with low pH and with low pH compatible conservation systems are another aspect of the present invention.
[061] The use of these milder glutamate surfactants at relatively high levels also makes it possible to use lesser amounts of cotensoatives (for example, anfoacetate, CAPB). It can be seen that the anfoacetate maintains a wider isotropic region than the CAPB (Tables 1 and 2 versus Table 3). Similarly, the CAPHS and coconut betaine maintain a larger isotropic region than the CAPB (Tables 4 and 5 versus This is especially important for fully formulated isotropic compositions.
[062] When using a mixture of C10 and Ccoco (see, for example, Table 2), which can be preferably in the present invention, compared to the mixture of C10 and C12 (Table 1) an isotropic region is achieved using lower amounts of C10 glutamate. That is, less C10 is needed to reach a soluble region (which also helps in foaming). The systems with the most cototensive amphoteric glutamate, therefore, are preferably (for example, the amphacetate or beta-amine of amidopropyl). The non-ionic surfactant is an additional co-active preferably in a glutamate / co-active system.
[063] Our examples show that changing the chain length distribution in the glutamate surfactant can also provide the preferred isotropic compositions. Therefore, as the use of glutamate is intensified and the amount of co-surfactant is minimized, the amount of lower chain length glutamate (eg C8, C10) can be reduced while still obtaining the clear pH isotropic compositions low. Using more glutamate of higher chain length (for example, C12 to C20) also helps to maintain good foaming values.
[064] As indicated above, while C10 should be minimized, depending on specific surfactant systems, in some embodiments of the present invention, the ratio of C10 to C12 should be at least 1/5, possibly 1/3 and above ( although preferably not more than 1/1) to ensure the formation of isotropic compositions, as defined.
[065] Preferably stable isotropic compositions are those with a ratio of C10 / C12 acyl glutamate of about 1/3 and above and with a lauroamfoacetate / acyl glutamate ratio of about 1/7 and above (up to 1 /1). To ensure good foaming performance and minimize costs, the proportion of acyl glutamate C10 / C12 is preferably 1/1 and lower (preferably above 1/3) and the proportion of lauroamfacetate / glutamate of acyl must be 1/1 or less.
[066] Therefore, there is the desired benefit obtained from compositions preferably with enhanced glutamate (using less co-surfactant) and larger amounts of higher chain glutamate (better foaming, especially good since there is less co-surfactant). Again , the enhanced foaming benefit from compositions based on isotropic surfactant chassis is seen if the final formulations are isotropic or anisotropic.
[067] Preferably, glutamates should be used in a concentration of greater than or equal to 50% of the surfactant system, more preferably, greater than or equal to 60%, even more preferably, greater than or equal to 70%.
[068] A composition that can be used comprises an amount greater than or equal to 50% of alkali metal (C8-C14) glutamate and alkaline amfoacetate, preferably lauroamfoacetate. The composition may comprise a mixture of C10 and C12 glutamate or C10 and Ccoco (Ccoco glutamate is glutamate with the distribution of the length of the cocoyl chain, as defined above). Preferably, mixtures of C10 and Ccoco if it is desired to minimize the content of C10 since the longer chain lengths elevated ones usually provide better foaming. Like the mixture of C10 and Ccoco, it preferably has a C8-C10 chain length distribution where C8-C10 is present in an amount greater than 13%, preferably greater than 15% of all R groups in the glutamate salt as defined above.
[069] In addition to the absolute amounts of co-surfactant (preferably to minimize), in some specific compositions we can define the approximate minimum proportions of co-surfactant for the glutamate necessary to ensure isotropic formation. Therefore, in anfoacetate / glutamate systems, ratio of anfoacetate to glutamate is preferably about 1/7 and higher (up to 1/1) to maximize the isotropic region. This may depend on the lengths of the glutamate chain, and another preferred system is where the mixture of decanoyl and lauroyl glutamate is used and the ratio of anfoacetate to glutamate is 1 to 1.7 and higher (preferably the glutamate is the primary global surfactant).
[070] Preferably stable isotropic compositions are those with a ratio of C10 / Ccoco acyl glutamate of about 1/3 and above and with a lauroamfoacetate / acyl glutamate ratio of about 1/7 and above. To ensure good foaming performance, minimize costs and observe an increased viscosity, the proportion of acyl glutamate C10 / Ccoco is preferably 1/1 and below (preferably about 1/3 and above) and the acyl lauroamfoacetate / glutamate ratio should be 1 / 1.7 or less.
[071] Another composition that can be used (although not preferably) comprises an amount greater than or equal to 50% of glutamate and betaine, for example, cocoamidopropyl betaine. In such systems, glutamate comprises an amount greater than or equal to 60% of the surfactant system, more preferably, greater than or equal to 75%, even more preferably, greater than or equal to 80%.
[072] In a preferred system of the present invention, the ratio of anfoacetate to glutamate can be 1/19 and higher (preferably, glutamate is the primary surfactant). In this system, less co-surfactant is needed to optimize the isotropic region (for example, compared to the use of cocoamidopropyl betaine).
[073] Similarly, another preferred embodiment comprises a surfactant system that is a mixture of CAPHS and glutamate and in which the ratio of CAPHS to the glutamate salts is as low as 1/19 and higher (up to 1/1 ).
[074] In general, the preferred compositions are those in which the glutamate salt is selected from the group consisting of glutamate C10, C12 and Ccoco and their mixtures. In a mixture comprising Ccoco, the mixture preferably has a C8-C10 chain length distribution where C8-C10 is present in an amount greater than 13%, based on all R chain lengths in the salts of glutamate. In such a general composition, preferably, the anfoacetate is the co-active and, preferably, the ratio of anfoacetate to glutamate is 1/7 and higher, more preferably, 1/7 to 1/1. Another preferred co-active agent is one selected from the group consisting of betaine, sultaine and their mixtures, where the proportion of the co-active agent for glutamate is 1/19 and higher, preferably from 1/19 to 1/1
[075] Preferably stable isotropic compositions are those with a proportion of C10 / Ccoco acyl glutamate (using CAPHS, less co-active is required to obtain the isotropic region compared to certain other co-active agents, for example, CAPB or anfoacetate) about 1/7 and above and with a CAPHS / acyl glutamate ratio of about 1/19 and above. To ensure good foaming performance, minimize costs and observe an increased viscosity, the ratio of acyl glutamate C10 / Ccoco is preferably 1/1 and lower and the ratio of CAPHS / acyl glutamate is preferably 1/1 or less. SKIN OR HAIR BENEFIT AGENTS
[076] In the same composition as the present invention, from 0 to 30% by weight, preferably from 0.1 to 10%, more preferably, from 0.1 to 5% by weight of the skin or hair benefit agent Is it used. As the person skilled in the art will understand, in the present composition, the beneficial agent is a different compound from the surfactants indicated under the surfactant system. Therefore, preferably, the benefit agent is preferably not a surfactant. Preferably, the benefit agent is an oil-soluble emollient or hydrating oil. These are molecules that increase hydration through various mechanisms that may include preventing water loss (occlusive agents), attracting moisture (humectants); or that restore the skin's natural moisturizing factors (for example, amino-lipids). Preferably moisturizers include petrolatum and silicone. Preferably, the moisturizer is a vegetable oil or triglyceride. Oils preferably include sunflower seed oil and soybean oil. The moisturizer can be a long chain fatty acid ester [C14-C30], such as isopropyl palmitate.
[077] Some naturally restoring agents and moisturizers include: (a) vitamins such as vitamin A and E, and vitamin alkyl esters such as vitamin C alkyl esters; (b) lipids such as cholesterol, cholesterol esters, lanolin, sucrose esters and pseudoceramides; (c) liposome-forming materials such as phospholipids and suitable amphophilic molecules that have two long hydrocarbon chains; (d) essential fatty acids, polyunsaturated fatty acids and sources of these materials; (e) triglycerides of unsaturated fatty acids such as sunflower oil, evening primrose oil, avocado oil, almond oil; (f) vegetable butters formed from mixtures of saturated and unsaturated fatty acids such as Shea butter; (g) minerals such as sources of zinc, magnesium and iron; and (h) silicone oils, gums, their modifications, such as linear and cyclic polydimethylsiloxanes, amino silicone oil, alkyl and alkylaryl.
[078] Water-soluble benefit agents may also be used. Water-soluble agents preferably include glycerin, sorbitol, polyalkylene glycols and mixtures thereof.
[079] If used, depending on the quantity and miscibility of the beneficial agent in the isotropic surfactant chassis, the chassis can still maintain clarity. However, even if the beneficial agent makes the chassis anisotropic, the low pH and foaming benefits discussed above are still retained.
[080] Although the compositions of the present invention do not require external structuring agents, when using the oil-soluble benefits, as mentioned above, it is preferable to use the structuring agents. STRUCTURING
[081] Preferably, the compositions of the present invention comprise from 0.1 to 10% by weight, preferably from 0.5 to 7% by weight of a structurant. The structuring agent can be a water-soluble or water-dispersible polymer which can be a cationic, anionic, amphoteric or non-ionic polymer to enhance viscosity.
[082] Examples of water-soluble or water-dispersible polymers include carbohydrate gums such as cellulose gum, microcrystalline cellulose, cellulose gel, hydroxyethyl cellulose, hydroxypropyl cellulose, sodium carboxymethyl cellulose, hydroxymethyl cellulose or carboxymethyl cellulose , methyl cellulose, ethyl cellulose, guar gum, karaya gum, tragacanth gum, arabic gum, acacia gum, agar gum, xanthan gum and mixtures thereof; modified and unmodified starch granules with gelatinization temperature between 30 to 85 ° C and water-soluble starch in cold water and pre-gelatinized; polyacrylate; carbopol; alkaline soluble emulsion polymers such as Aculyn 28, Aculyn 22 or Carbopol Aqua SF1; cationic polymers, such as modified polysaccharides, including the cationic guar available from Rhone Poulenc under the trade name Jaguar C13S, Jaguar C14S, Jaguar C17 or Jaguar C16, BF Guar C17 from Lamberti, Aqua D4091 or Aqua D4051 from Aqualon; cationic modified cellulose such as Amerchol's UCARE Polymer JR30 or JR40; N-Hance 3000, N-Hance 3196, N-Hance CPX215 or N-Hance GPX 196 from Hercules; synthetic cationic polymer such as Nalco's Merquat 100, Merquat 280, Merquat 281 and Merquat 550; cationic starches, for example, StaLok® 100, 200, 300 and 400 produced by Staley Inc .; cationic galactamannans based on guar gum from the Galactasol 800 series from Henkel, Inc .; Quadrisect Um-200 and Polyquaternium-24.
[083] Gel-forming polymers such as modified or unmodified starch granules, xanthan gum, Carbopol, emulsion polymers soluble in alkaline solutions and cationic guar gum, such as Lamberti BF Guar C17 and cationic modified cellulose, such as UCARE Polymer JR 30® or JR 40® are especially preferred for the present invention.
[084] A structuring copolymer preferably is the polymerization product (for example, the additive polymerization product) of (1) a first ethylenically unsaturated monomer; (2) a second ethylenically unsaturated monomer; (3) the (meth) acrylate monomer and (4) the associative monomer (in general, of random structure, preferably the copolymers are linear).
[085] The first monomer of (1) can be the diacid of Formula: -HOOC-CR1 = CR2-COOH (I), -a precursor of cyclic diacid anhydride (I), the anhydride that has the Formula:
-and their combinations, -in which R1 and R2, individually, are selected from H, C1-C3 alkyl, phenyl, chlorine and bromine and, in one or more embodiments, are preferably individually selected from H and C1-C3 alkyl.
[086] Preferably monomers include maleic acid and maleic acid anhydride. It may comprise from 0 to 10%, preferably from 0.1 to 5% by weight of the total monomer charge.
[087] The second monomer (2) can be acrylic acid, methacrylic acid and their combinations. It can be used from 15 to 60% by weight based on the total monomer charges.
[088] The third (meth) acrylate monomer can be C1-C8 alkyl esters of acrylic acid, C1C8 methacrylic acid alkylalkyl esters and combinations and can be 30 to 75% by weight based on the total monomer charge. (a) The associative monomer has the Formula: -R4-CH = C (R3) -C (O) -O- (R5O) a-R6 (III) -in which: -R3 and R4, independently, are selected at from H and C1-C3 alkyl, each R5O independently is an oxyalkylene unit containing from 2 to 4, preferably from 2 to 3 carbon atoms, -R6 is selected from: -linear and branched alkyl containing from 8 to 40, preferably from 8 to 30, more preferably from 10 to 22 carbon atoms, and -alkyl, whose alkyl group contains from 8 to 40, preferably from 8 to 30, more preferably from 10 at 22 carbon atoms, that group being straight or branched alkyl, said alkaryl, preferably being alkylphenyl; and -a has a value of 6 to 40, preferably 15 to 35, more preferably 20 to 30.
[089] Of particular interest, in one or more embodiments, is an associative monomer of Formula: -CH3 [CH2] b-CH2- [OCH2CH2] aOC (O) C (R3) = CH (R4) (IV) -em whereas R3, R4 and a are as described above, and b has a value from 6 to 38, preferably from 6 to 28 and, most preferably, from 8 to 20.
[090] In the monomers of Formula III and Formula IV, R3 is preferably a methyl group and R4 is preferably H. In the associative monomers described above, a and b represent the number of their respective oxyalkylene repeating units and -CH2- and in general, are whole numbers. In one or more realizations of interest, a is greater than or equal to b.
[091] The associative monomer can be used in amounts from 1 to about 25% by weight, preferably from 2 to 20% by weight and, most preferably, from 2 to 15% by weight based on the total monomer added . In one or more embodiments of special interest, the amount of associative monomer used is 5 to 12% by weight based on the total monomer added.
[092] In some compositions, it has been found that a structuring agent that is especially effective for maintaining clarity and stability is the copolymer with the following Formula:
-where a, b, c, d and d represent the percentage by weight that each monomer repeat unit is contained within the copolymer; -A is a polyacidic vinyl monomer selected from the group consisting of maleic, fumaric, itaconic, citraconic acid and their combinations and anhydrides and their salts; and -B is acrylic or methacrylic acid or a salt thereof; -C is a C1-C8 ester of acrylic acid or methacrylic acid; -D is an associative monomer of Formula (VI)
-in which each R2, independently, is H, methyl, -C (= O) OH, or -C (= O) OR3; -R3 is C1-C30 alkyl; -T is -CH2C (= O) O -, - C (= O) O-, -O-, -CH2O-, -NHC (= O) NH -, - C (= O) NH -, - Ar- (CE2) z-NHC (= O) O -, - Ar- (CE2) z-NHC (= O) NH-or - CH2CH2NHC (= O) -; -Ar is the divalent arila; -E is H or methyl; -z is 0 or 1; -k is an integer in the range from 0 to 30; em is 0 or 1; - with the proviso that when k is 0, m is 0, and when k is in the range 1 to 30; m is 1; - (R4O) n is polyoxyalkylene, which is a homopolymer, a random copolymer or a block copolymer of C2C4 oxyalkylene units, where R4 is C2H4, C3H6, C4H8, or a mixture thereof, and n is an integer in the range from 5 to 250; -Y is -R4O-, -R4H-, -C (= O) -, -C (= O) NH-, R4NHC (= O) NH- or - C (= O) NHC (= O) -; and -R5 is the substituted or unsubstituted alkyl selected from the group consisting of linear C8-C40 alkyl, branched C8-C40 alkyl, carbocyclic C8-C40 alkyl, C8-C40 alkyl substituted by alkyl, phenyl, C8-C40 alkyl aryl-substituted and ester of the C8-C80 complex; wherein the alkyl group R5 optionally comprises one or more substituents selected from the group consisting of hydroxy, alkoxy and halogen; and -E when present is a crosslinking monomer for introducing branching and for molecular weight control, comprising the crosslinking monomer comprising the polyfunctional units that carry multiple reactive functionalization groups selected from the group consisting of vinyl, allyl and their functional mixtures, groups A, B, C, D and E being covalently linked together in a selected way from a random, block or cross copolymer format.
[093] The amounts of "a" can vary from about 0 to 10%, preferably from 0.1 to about 5% by weight; the amounts of "b" can vary from about 10 to about 80%, preferably from 15 to 60% by weight; the amounts of "c" can vary from about 30 to about 85%, preferably from 30 to 75% by weight; the amounts of "d" can vary from about 1 to about 25% by weight; and the amounts of "e" can vary from 0 to about 5% by weight of the total copolymer.
[094] Some compositions may contain water-soluble polymers in amounts of 0.005 to 5% by weight.
[095] Examples of water-soluble polymers include high molecular weight polyethylene glycols such as Polyox® WSR-205 (PEG 14M), Polyox® WSR-N-60K (PEG 45M) and Polyox® WSR-301 (PEG 90M); carbohydrate gums, such as cellulose gum, hydroxyethyl cellulose, hydroxypropyl cellulose, sodium carboxymethyl cellulose, methyl cellulose, ethyl cellulose, guar gum, karaya gum, tragacanth gum, arabic gum, acacia gum , agar gum and xanthan gum; granules of modified starch and water-soluble starch in cold water and pre-gelatinized; cationic polymer such as modified polysaccharides including the cationic guar available from Rhodia under the trade name Jaguar®; cationic modified cellulose such as Amerchol's UCARE Polymer JR30 or JR40; N-Hance® 3000, N-Hance® 3196, N-Hance® GPX 215 or N-Hance® GPX 196 from Hercules; synthetic cationic polymers such as Merquat® 100, Merquat® 280, Merquat® 281 and Merquat® 550 marketed by Nalco. Water-soluble polymers can be used individually or as combinations of two or more polymers of the same or different classes. The high molecular weight polyethylene glycols Polyox® WSR-301 (PEG 90M) and Polyox® WSR-N-60K (PEG 45M) and guar derivatives such as Jaguar® S, Jaguar® C17 and Jaguar® C13 and synthetic cationic polymers such like Merquat® 100 are especially desired. CONSERVATIVES
[096] Personal product formulations provide a good medium for the growth of microbes. Microbial action can manifest itself in terms of hydrolysis, oxidation or reduction and can cause odors, color changes, adverse pH changes, rupture of emulsions and changes in product texture. Therefore, good conservation systems are needed to prevent microbial growth, product deterioration and infection of the skin and hair. The preservative must be effective against Gram-negative and Gram-positive bacteria, as well as fungi (mold and yeast).
[097] An effective preservative is a chemical agent that will prevent microbial growth in the product, making it safe and increasing its shelf life.
[098] The ideal conservation system should provide broad spectrum activity and be effective over the life of the product. As the microorganisms multiply in the aqueous phase of the formulations, they must also be water-soluble. When the formulations contain appreciable levels of oils, the system should favor the partition in the aqueous phase. Ideally, the conservation system should be effective over a wide pH range, colorless and safe to use.
[099] It should be non-irritating, non-sensitizing and, preferably, non-poisonous. Ideally, when eliminating pathogenic organisms in the formulation during storage, you should leave the symbiotic organisms on the skin alone after applying the formulation to the skin, hair or mucous membrane.
[0100] Some preservatives preferably include: (1) parabens, for example, methyl-, ethyl-, propyl-, iso-butyl- and butyl-paraben; (2) formaldehyde-releasing preservatives, for example, formaldehyde, quaternium-15, dimethyl-dimethyl (DMDM) hydantoin, imidazolidinyl urea, diazolidinyl urea, sodium hydroxymethylglycinate and 2-bromo-2-nitropropane-1,3-diol ; (3) isothiazolones, such as chloromethyl isothiazolinone (CMIT), methyl isothiazolinone (MIT) or benzisothiazolinone (BIT); (4) halogenated organic active products, such as idopropynyl butylcarbamate and methyl-dibromo glutaranitrile; (5) organic acids such as benzoic acid, dehydroacetic acid, salicylic acid, lactic acid and sorbic acids; (6) others, including chloroacetamide, phenyloxyethanol and triclosan.
[0101] Additional suitable preservatives for personal care products can be found in “Preservatives for Cosmetics Manual, 2nd edition”, by David S. Steinbens, 2006 and in “Preservatives for Cosmetics”, DC Steinberg, Allured Publishing Corp., ISBN # 0-93170- 54-5. Such agents are normally used from 0.1 to 1%, more preferably from 0.5 to 0.7% of the personal product formulation.
[0102] The organic acids observed are especially preferred. Especially preferably, organic acids containing pKa are between about 4.0 and 5.5, preferably between 4.0 and 5.0.
[0103] No preservative is ideal for all situations. For example, parabens are relatively non-irritating, but they partition in favor of the oil phase and are inactivated by some surfactants. Preservatives that maintain formaldehyde have a broad spectrum of effectiveness, but are irritating and banned in some countries.
[0104] The compositions of the present invention, which preferably have a pH of about 3 to 5.1, preferably will comprise the organic acids indicated above as preservatives. Specifically, preferably, it is the organic acids which have a pKa of 4.0 to 5.5, preferably of 4.2 and 5.1.
[0105] More specifically, the compositions preferably have a pH that is less than one pH unit, more preferably, less than 0.5 pH units, above pKa of organic acid. Within such a tight pH range, the organic acid will largely remain in the non-dissociated form which is the form required for activity against the agent's microorganisms.
[0106] Therefore, for example, since the pKa of benzoic acid is 4.2, ideally it is suitable for use in the low pH to 5.2 composition (according to the preferred embodiments of the present preferably) at or below 4.7.
[0107] As indicated, benzoic acid is a preferred preservative.
[0108] Optionally, the compositions of the present invention can still comprise one or more additional ingredients. Non-limiting examples of such additional ingredients, for example, are dyes, pigments, opacifiers, fragrances (encapsulated or present as free fragrances), emotive oils, vitamins and vitamin derivatives, abrasives, optical agents (including, for example, reflective particles and interference pigments), pH adjusters, plant extracts, essential oils, preservatives, antioxidants, antimicrobials, viscosity modifiers, humectants, beard wetting agents, sensory agents, fatty acid soap and skin benefit agents and / or hair (for example, aloe, panthenol, alpha-hydroxy acids, phospholipids, botanical oils and amino acids to name a few). The selection and quantity of any additional individual ingredient depends on factors including the special ingredient, the desired properties and the intended use of the composition in which it is employed. For example, the fragrance is normally used in an amount of 0.1 to 3.0% by weight of the composition, or more. For many compositions, the total amount of these additional ingredients is 0.01 to 30% by weight, more especially, from 0.1 to 15% by weight, even more especially, from 1 to 10% by weight, based on weight total composition.
[0109] In one or more embodiments, the total amount of these additional optional ingredients is 0.5 to 5% by weight. Other ingredients, for example, fatty acid soaps, can be present at levels up to 10% by weight, based on the total weight of the composition.
[0110] The compositions are water based and normally comprise 30 to 90% by weight of water. Water is the balance after all the ingredients mentioned above have been counted. PROTOCOLS CLARITY
[0111] The transparency (clarity) of a sample is measured by measuring the optical absorbance at the wavelength of À = 550 nm. Fully formulated samples (about 300 pI) are added to a 96-well plate without dilution and read by a microplate reader (SpectraMax® 340PC, Molecular Device). An ideally clear sample has zero absorbance (ie 100% transmission). In the present invention, a sample with an absorbance of less than 0.5, more preferably, less than 1, most preferably less than 0.5, even more preferably, less than 0.2, is defined as providing transparency visually acceptable (clarity). EXAMPLES
[0112] The demonstration systems were built by weighing pre-determined masses of surfactants in a tared glass beaker. Depositors prepared the sample systems on a 50 g scale with 15% total surfactant. The desired mixture of Glutamate surfactants were weighed first, followed by any co-surfactants. The total level of surfactant and co-active was always 7.5 g. then, a charge of citric acid was added, calculated to be sufficient to produce a final pH of about 4.5. The system was then prepared up to 50 g with water and heated with stirring to 75 ° C. After 5 to 15 minutes of stirring, the resulting single-phase isotropic system was removed from the heat and allowed to cool to room temperature. Once cooled, the pH was adjusted to pH 4.5 with the 50% citric acid solution and water was added to replace any loss during heating. The systems were equilibrated for two weeks at room temperature before the observations used in the construction of the phase maps.
[0113] In order to demonstrate the compositions comprising a surfactant system in which glutamate is the primary surfactant, Depositors have prepared several systems comprising (1) mixtures of C10 / C12 glutamate and anfoacetate; (2) mixtures of C10 / Ccoco glutamate and anfoacetate; (3) mixtures of C10 / Ccoco glutamate and cocoamido propyl betaine (CAPB); (4) mixtures of C10 / Ccoco glutamate and cocamidopropyl hydroxy-sultaine (CAPHS); and (5) mixtures of C10 / Ccoco glutamate and coconut betaine.
[0114] Results are presented as shown below. EXAMPLE 1
[0115] The Stability Map of the lauroyl glutamate / anfoacetate system for 15% of total surfactant and pH 4.5. The lauroyl glutamate was mixed with the decanoil glutamate, as indicated. Symbol I = isotropic system with an absorbance value at 550 nm below 0.2, X = two-phase system. In these systems, the left column represents the percentage (%) of C10 in relation to the percentage (%) of C10 and C12, so that, for example, 75 represents a system in which 75% of the total glutamate present is C10 and 25% is C12. The top row is the percentage (%) of anphosphate with the balance being glutamate. Therefore, 12.5 represents a system in which 87.5% of the surfactant is the glutamate mixture and 12.5% is the anphacetate. The total surfactant present is 15% in all cases, the remainder being water with a lower amount of citric acid.TABELA 1

[0116] It will be noted that, for this Example, the stable isotropic compositions are preferably those with a ratio of C10 / C12 acyl glutamate of about 1/3 and above and with a ratio of lauroamfoacetate / acyl glutamate of about 1 / 1.7 and above. To ensure good foaming performance, minimize costs, the proportion of acyl glutamate C10 / C12 should be 1/1 and lower, preferably above 1/3 and the proportion of lauroamfacetate / acyl glutamate should be 1/1 or less. EXAMPLE 2
[0117] The Stability Map of the coconut glutamate / anfoacetate system for 15% of total surfactant and pH 4.5. Cocoyl glutamate was mixed with decanoil glutamate as indicated. Symbol I = isotropic system with an absorbance value at 550 nm below 0.2, X = two-phase system. Percentages are measured as shown in Table 1 of Example 1. TABLE 2

[0118] It will be noted that stable isotropic compositions are preferably those with a ratio of C10 / Ccoco acyl glutamate of about 1/3 and above and with a ratio of lauroamfoacetate / acyl glutamate of about 1/7 and above . To ensure good foaming performance, minimize costs and observe an increased viscosity, the proportion of acyl glutamate C10 / Ccoco should be 1/1 and below (preferably about 1/3 and above) and the proportion of lauroamfoacetate / acyl glutamate should be 1 / 1.7 or less. EXAMPLE 3
[0119] The Stability Map of the cocoyl glutamate / CAPB system for 15% of total surfactant and pH 4.5. Cocoil glutamate was mixed with decanoil glutamate, as indicated. Symbol I = isotropic system with an absorbance value at 550 nm below 0.2, X = two-phase system. The percentages are measured as shown in Table 1.TABLE 3

[0120] As seen from Examples 1 to 3, when using a mixture of C10 and Ccoco (Table 2) compared to the mixture of C10 and C12 (Table 1), an isotropic region is achieved using much more quantities low C10 glutamate. That is, less C10 is needed to reach a soluble region (which also helps in foaming). The systems are glutamate plus the co-active (for example, the amphacetate or betaine of cocoamidopropyl). The non-ionic surfactant is preferably a surfactant in a glutamate / cotensoative system. When the co-active agent used is CAPB instead of anfoacetate (Table 3 versus Table 2), some solubility benefit at a lower level of C10 is lost. Even when solubility is lost, however, the benefits of low pH (for alternative conservation systems) and foaming using the high glutamate surfactant chassis are maintained. EXAMPLE 4
[0121] The Stability Map of the cocoyl glutamate / cocamidopropyl hydroxy-sultaine system (CAPHS) for 15% of total surfactant and pH 4.5. Cocoil glutamate was mixed with decanoil glutamate, as indicated. Symbol I = isotropic system with an absorbance value at 550 nm below 0.2, X = two-phase system. The percentages are measured as indicated in Table 1.TABLE 4

[0122] It will be noted that stable isotropic compositions are preferably those with a proportion of C10 / Ccoco acyl glutamate (using CAPHS, less co-active is required to obtain the isotropic region compared to certain other co-active agents, for example, CAPB or anfoacetate) of about 1/7 and higher and with a CAPHS / acyl glutamate ratio of about 1/19 and higher. To ensure good foaming performance, minimize costs and observe an increased viscosity, the ratio of acyl glutamate C10 / Ccoco should be 1/1 and lower and the ratio of CAPHS / acyl glutamate should be 1/1 or bottom. EXAMPLE 5
[0123] The Stability Map of the cocoyl / cocobetaine glutamate system for 15% of total surfactant and pH 4.5. Cocoyl glutamate was mixed with decanoil glutamate as indicated. Symbol I - isotropic system with an absorbance value at 550 nm below 0.2, X = two-phase system. The percentages are measured as indicated in Table 1.TABLE 5

[0124] It will be appreciated that stable isotropic compositions are preferably those with a ratio of C10 / Ccoco acyl glutamate of about 1/7 and higher and with a ratio of betaine coconut glutamate / acyl glutamate of about 1 / 19 and higher (less co-active is required to obtain the isotropic regions compared to the use of other co-active agents). To ensure good foaming performance, minimize costs and observe an increased viscosity, the C10 / Ccoco glutamate acyl ratio must be 1/1 and lower and the ratio of coconut betaine / acyl glutamate must be 1/1 or lower.
[0125] As can be seen from Examples 2, 4 and 5, when a mixture of C10 and Ccoco glutamates is used together with a co-surfactant selected from the list of preference, of amphoteric surfactants, a wide, isotropic region results and stable. More specifically, mixing the shortest chain length glutamates (decanoyl glutamate) with the longest chain length glutamates (cocoyl glutamate) produces the isotropic systems at pH 4.5, where the glutamate comprises 100% of the system surfactant. In addition, the addition of amphoteric co-surfactants preferably to glutamate mixtures results in isotropic systems in which glutamate comprises an amount greater than or equal to 50% of the surfactant system and 100% of the total anionic surfactant while enabling a richer mixture of glutamate. longer chain lengths, which intensifies foaming. Again, even when the benefit agents in the final system can form the anisotropic compositions, the foaming benefits are retained. EXAMPLES 6 TO 8
[0126] For Examples 6 to 8, the finished formulations were prepared by adding the surfactants, starch and 70% of the free water in a tared container immersed in a water bath and with a superior mixture. The components are stirred until uniformly mixed and then stirring continues as the water bath temperature is raised to 70 ° C. Once at temperature, Jaguar (predispersed in glycerin) and PEG are added together with citric acid. Cooling is started and the other components added once the water bath reaches 35 ° C. The final pH and water content are therefore adjusted.


[0127] Example 6 is typical of a conventional conservation system, which can be used over a wide pH range, but whose application is regionally restricted. In contrast, Example 7 illustrates a conservation system that is preferably in these regions, but that will only work at pH 5.0 and below. The example formulation provides an effective product form for the practice of this conservation system. Both Examples produced the stable isotropic single-phase systems. Example 8 is an example of a finished formulation containing the optional benefit ingredients (Puregel® B990 in this case, a starch thickening agent) that make the final system anisotropic, although still stable against physical phase separation. EXAMPLES 9-11
[0128] For Examples 9 to 11, the finished formulations were prepared as described for Examples 6 to 8.


1 This is a copolymer which is the polymerization product of (by weight of the total polymer) (a) about 40 to 70% ethyl acrylate; (b) 20 to 50% methacrylic acid; (c) 0.1 to 3% maleic anhydride and; (d) 2 to 15% of an associative monomer (for example, Component D of Formula V defined above). Example 9 is typical of a conventional conservation system, which can be used over a wide pH range, but whose application is regionally restricted. In contrast, Example 10 illustrates a conservation system that is preferably in these regions, but that will only work at pH 5.0 and below. The example formulation provides an effective product form to practice the conservation system. Both Examples produced a stable, isotropic, single-phase surfactant chassis. Example 10 is an example of a finished formulation containing optional benefit ingredients (soy oil and hydrogenated soy oil in this case, an emollient oil) that make the final system anisotropic, although still stable against physical phase separation. Similarly, Example 11 is an example of a finished formulation containing optional benefit ingredients (petrolatum and polybutene, an emollient oil and sensory modifier, respectively ) that make the final system anisotropic, although still stable against physical phase separation.

权利要求:
Claims (15)
[0001]
1. CLEANING COMPOSITION, characterized by comprising: (a) from 0.5 to 35% in total weight of the composition of a surfactant system comprising an anionic surfactant comprising an acyl glutamate salt, in which the glutamate salt of acila is present in 50% or more of all surfactants present, - and in which the surfactant system still comprises from 0 to 20% in total weight of the composition of a co-surfactant, where co-surfactants are surfactants that are not anionic, selected from the group consisting of non-ionic, cationic, amphoteric surfactants and their mixtures; (b) from 0% to 30% by weight of the total composition of water-soluble or oil-soluble skin or hair benefit agent other than a surfactant; (c) from 0.01 to 1% of an organic acid selected from the group of organic acids that have pKa between 4.0 and 5.5, where the organic acid is largely in the non-dissociated form; and (d) water (e) where the pH is 5.1 or lower and where (f) the glutamate salt comprises a mixture of C10 and Ccoco glutamate, where the mixture of C10 and Ccoco has a distribution chain length C8-C10, where C8-C10 is present in an amount greater than 13%, or (g) the glutamate salt comprises a mixture of glutamate C10 and C12, where the ratio of C10 to C12 is, at least 1/5, (h) where the glutamate salt has a cation that is sodium or potassium.
[0002]
2. COMPOSITION, according to claim 1, characterized by the composition being clear, in which the clarity is defined by the absorbance value of 1.0 or less when measured at a wavelength of 550 nm, when 300 pI are added in a 96-well plate without dilution.
[0003]
3. COMPOSITION, according to any one of claims 1 to 2, characterized in that it comprises from 0.5 to 15% of the surfactant.
[0004]
4. COMPOSITION, according to any one of claims 1 to 3, characterized by the co-surfactant comprising an amphoteric surfactant.
[0005]
5. COMPOSITION, according to any one of claims 1 to 4, characterized in that it additionally comprises from 0.1% to 5% by weight of the beneficial agent, not being a surfactant.
[0006]
6. COMPOSITION according to any one of claims 1 to 5, characterized in that said benefit agent is an oil-soluble emollient or hydrating oil.
[0007]
7. COMPOSITION according to any one of claims 1 to 6, characterized in that the pH of the composition is 3.0 to 5.0.
[0008]
8. COMPOSITION, according to claim 7, characterized by the pH being 3.5 to 5.0.
[0009]
9. COMPOSITION, according to any one of claims 1 to 8, characterized in that it additionally comprises a structuring agent.
[0010]
10. COMPOSITION, according to claim 9, characterized by comprising a structurant of Formula:
[0011]
11. COMPOSITION, according to claim 1, characterized by being with the immiscible benefit agent.
[0012]
12.COMPOSITION, according to claim 1, characterized by the acyl glutamate salt selected from the group consisting of C10, C12 and Cococoemixtures of the same, the co-active agent being the anfoacetate and anfoacetate ratio for the glutamate salt being 1/7 and higher.
[0013]
13.COMPOSITION, according to claim 12, characterized by the proportion being 1/7 to 1/1.
[0014]
14. COMPOSITION, according to any one of claims 1 to 11, characterized in that the glutamate salt is selected from the group consisting of glutamate C10, C12 and Ccoco, and mixtures thereof, the co-active agent is selected from the group consisting of betaine, sultaine and mixtures thereof and the proportion of the co-active agent for glutamate is 1/19 and higher.
[0015]
15. COMPOSITION, according to claim 14, characterized in that the proportion is from 1/19 to 1/1.

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2020-10-27| B09A| Decision: intention to grant [chapter 9.1 patent gazette]|

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2020-12-08| B16A| Patent or certificate of addition of invention granted|Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 12/11/2015, OBSERVADAS AS CONDICOES LEGAIS. |

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2021-07-27| B25A| Requested transfer of rights approved|Owner name: UNILEVER IP HOLDINGS B.V. (NL) |

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